Cosmetic Ingredients in stock Full-time Job

Cosmetic Ingredients in stock Product Description 聽 Quercetin is widely found in the stems, skins, flowers, leaves, buds, seeds and fruits of many plants, mostly in the form of glycosides, such as rutin, quercitrin, hyperin, etc. Quercetin can be obtained by acid hydrolysis. Quercetin powder, as a natural flavonoid widely existing in nature, has been deeply studied. At present, it has been found that it has multiple biological activities, such as antioxidant, antiviral and anti-inflammatory. It can be used to treat liver, heart, spleen, lung, kidney, orthopedic diseases and nervous system diseases in cell and animal experiments. 聽 Product Specification 聽 ItemSpecificationResultTest Method Physical and Chemical Parameters Assay by HPLC鈮?5.0%95.68%HPLC Loss on Drying鈮?2.0%10.47%5g/120鈩?/p> Sulphated Ash鈮?.30%0.26%CP2015 Bulk density鈮?.20gm/cc0.23gm/ccCP2015 Tapped Density鈮?.30gm/cc0.35gm/ccCP2015 AppearanceYellow powderconformsVisual Sieve95% pass through Sieve # 80 meshconformsCP2015 Heavy Metals Total Heavy Metals鈮?0ppmConformsAtomic Absorption Lead鈮?ppm0.42ppmAtomic Absorption Arsenic鈮?ppm0.35ppmAtomic Absorption Mercury鈮?ppm0.05ppmAtomic Absorption Cadmium鈮?ppm0.09ppmAtomic Absorption Residual Solvent鈮?000mg/kg105mg/kgGC Microbiological Tests Total Plate Count鈮?,000cfu/g100cfu/gCP2015 Total Yeast & Mold鈮?00CFU/g10cfu/gCP2015 Escherichia ColiNegativeConformsCP2015 Salmonella sppNegativeConformsCP2015 StaphylococcusNegativeConformsCP2015 Conclusion:Comform to specification 聽 Product Function 聽 1. Antioxidation Quercetin is a natural chelating agent, which can chelate iron in the body, reduce iron overload in the body, and reduce oxidative damage caused by iron overload. Quercetin has many effects such as antioxidation, scavenging free radicals, inhibiting lipid peroxidation, etc. It can resist oxidation and protect cardiovascular health. 聽 2. Protection of the heart Quercetin powder has the effects of lowering blood pressure, enhancing capillary resistance, reducing capillary fragility, reducing blood lipid, dilating coronary artery and increasing coronary blood flow. Quercetin can effectively reduce H2O2-mediated oxidative damage of myocardial cells, and then inhibit myocardial cell apoptosis. 聽 3. Antiviral activity Quercetin can significantly reduce the replication rate of hepatitis C virus. At the same time, it was found that the infectivity of virus particles treated with Quercetin decreased by 65%, which indicated that Quercetin affected the integrity of the virus. Further, it was confirmed by molecular experiments that Quercetin can play an antiviral role by preventing the up-regulation of diacylglycerol acyltransferase by hepatitis C virus and the typical localization of hepatitis C virus core protein on the surface of lipid droplets. 聽 4. Neuroprotection Studies have shown that quercetin can protect nerve cell lines from many oxidative substances or neurotoxic substances that cause oxidative stress of cells. Experiments have also found that taking 0.5-50 mg/kg quercetin orally can avoid neurotoxicity caused by nerve gas, heavy metals (such as lead, mercury, tungsten) and pesticides, and prevent cognitive dysfunction induced by high-fat diet in rats. Recent studies have also shown that quercetin can alleviate the symptoms of cognitive dysfunction in Alzheimer's mice. 5. Allergy, asthma and allergic diseases In vitro cell experiments have found that quercetin can inhibit histamine release from mast cells and basophils. In several guinea pig experiments, oral administration or inhalation can reduce asthma attacks, but there are no human studies on asthma and allergic diseases at present. 聽 Product Application 聽 1. Medicine It has good expectorant, antitussive and antiasthmatic effects. In addition, it has the functions of lowering blood pressure, enhancing capillary resistance, reducing capillary fragility, lowering blood lipid, dilating coronary artery and increasing coronary blood flow. 聽 2. Antioxidants Mainly used in oils, beverages, cold drinks and meat processing products. 聽 3. Natural dyes. Can be used as a dielectric dye. Used for wool and cotton, yellow with aluminum salt, olive yellow with chromium salt, orange with tin salt and olive green with iron salt. Soap fastness is very good and light fastness is moderate. 聽 Other Information 聽 1. Acute LD50 value The acute toxicity of Quercetin powder to animals is small, with LD50 of 10 ~ 50g/kg in rats. Oral administration of LD50 160mg/kg and subcutaneous injection of LD50 100mg/kg in mice. 聽 2. Low dose is non-toxic to rats and human body. The National Toxicology Agency of the United States added 1000 or 10000mg/kg quercetin to male rat feed and 40000mg/kg quercetin to female rat feed. No evidence of carcinogenesis was found in the 2-year experiment. In human trials, oral administration of 4g quercetin has no adverse reaction, while intravenous administration of 100mg quercetin has good tolerance. 聽 3. Metabolic test In the past, people always thought that quercetin was not easily absorbed by human body, but in recent years, many in vitro and in vivo experiments showed that the body could absorb a considerable amount of quercetin and its derivatives. 聽聽Cosmetic Ingredients in stock website:http://www.angelbiology.com/cosmetic-ingredients/